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Team develops new mouse model to shed light on the mystery surrounding Huntington’s disease onset
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Team develops new mouse model to shed light on the mystery surrounding Huntington’s disease onset

by University of California, Los Angeles The upper portion of the schematic illustrates generation of a novel mouse model of Huntington’s disease with long, uninterrupted CAG repeats. In the new model, the striatum shows RNA and protein toxicities originated from the pure CAG repeats, which lead to neuronal damage. Credit: UCLA Health/Yang Lab Researchers at...