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AI tools are designing entirely new proteins that could transform medicine
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AI tools are designing entirely new proteins that could transform medicine

Ewen Callaway An artificial-intelligence tool called RFdiffusion designed a protein that binds to the parathyroid hormone, shown in pink. Credit: Ian C. Haydon/UW Institute for Protein Design “OK. Here we go.” David Juergens, a computational chemist at the University of Washington (UW) in Seattle, is about to design a protein that, in 3-billion-plus years of...

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Beyond AlphaFold: AI excels at creating new proteins

Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design. In the new papers, biologists at the University of Washington School of Medicine show that machine learning can be used to create protein molecules much more accurately and quickly than previously possible. The scientists hope this...