by Jim Fessenden, University of Massachusetts Medical School sup-tRNAs suppress the mIdua-W401X mutation in HEK293 cells. Credit: Nature (2022). DOI: 10.1038/s41586-022-04533-3 Gene therapy researchers at UMass Chan Medical School have shown the first evidence that a suppressor transfer RNA (tRNA) therapy can restore protein production up to six months after treatment in a mouse model of the...
