by Rockefeller University Credit: Neuron (2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechanisms are the subject of ongoing research and debate. When it comes to Huntington’s disease, steadily accumulating evidence over the past 30 years has led to a model of molecular events that explains several key...
by Northwestern University Credit: Pixabay/CC0 Public DomainScientists at the UC San Francisco (UCSF) and Northwestern Medicine may have found a way around the limitations of engineered T cells by borrowing a few tricks from cancer itself. By studying mutations in malignant T cells that cause lymphoma, they zeroed in on one that imparted exceptional potency to...
by First Hospital of Jilin University Locally estimated scatter plot smoothing estimated risk of steatosis (panels A and B) and advanced fibrosis (panels C and D) according to the CLivDlab and CLivDnon-lab scores. The shaded area represents 95% CIs. The dashed vertical lines show the cutoffs of the CLivD score separating minimal-risk, low-risk, intermediate-risk and...
by Cornell University Credit: Unsplash/CC0 Public Domain When looking for medical information on the internet, having the precise terminology makes the search fairly straightforward. But what if the person doing the searching doesn’t know the exact terminology, or wants to see what other information may be available without using technical terms? Will internet queries yield any...
SCRIPPS RESEARCH INSTITUTE IMAGE: A TEAM AT SCRIPPS RESEARCH INVENTED A NEW METHOD, CALLED CATCH, THAT SHOWS HOW DRUGS HIT THEIR TARGETS IN THE BODY. CELLS TARGETED BY A DRUG (PARGYLINE SHOWN IN CYAN) CAN BE IDENTIFIED BY MULTIPLE ROUNDS OF IMMUNOLABELING (RED SHOWING NEURONS; YELLOW SHOWING DOPAMINERGIC/NORADRENERGIC NEURONS; BLUE SHOWING CELL NUCLEI). CREDIT: SCRIPPS...
by Columbia University School of Engineering and Applied Science Ionic communication: (Top left) Cross-sectional schematic illustration of an ionic communication device consisting of an implanted transmitter electrode pair inside biological tissue and a receiver electrode pair on the surface of the tissue. (Top right) Frequency responses of ionic communication highlighting is capacity to operate at...
by University of Illinois at Urbana-Champaign An illustration of the cold plasma-integrated otoscope (main figure) and the earbud (inset) for the potential treatment of middle ear infections. Credit: Jungeun Won Middle ear infections, also known as otitis media, affect more than 80% of the children in the U.S. In a new study, researchers have designed a miniaturized 3D-printed...
