by Tel-Aviv University A lung with breast cancer metastasis, surrounded by inflammatory complement protein: Cyan: Cell nuclei Red: Complement protein Green: blood vessels. Credit: Lea Monteran A new treatment developed at Tel Aviv University may significantly enhance the efficacy of chemotherapy in breast cancer patients, reducing the risk for lung metastasis following chemo from 52%...
by University of Calgary Credit: Pixabay/CC0 Public Domain People with inflammatory bowel diseases develop inflammation of the intestine that can cause thickening of the gut wall and life-threatening blockage of the intestinal tube. Twenty to 50 percent of people with Crohn’s disease and ulcerative colitis are affected over their lifetime by this poorly understood condition,...
JOHNS HOPKINS MEDICINE In a new study with obese mice, Johns Hopkins Medicine researchers say they have added to evidence that specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people. The protein, a cation channel known as TRPM7, is found in carotid bodies, tiny sensory...
by Karen Weintraub Credit: Unsplash/CC0 Public Domain Sarah Hayden owns a lot of turtlenecks. She also has chunky necklaces and tons of makeup—anything to cover up the blotchy white skin on her face, neck, hands and knees. When she was about 23, Hayden was diagnosed with vitiligo, a noncontagious skin condition that leads to the loss...
by Universitat Pompeu Fabra – Barcelona JZL184 administration regresses cardiac hypertrophy and the expression of cardiac Cnr1 alterations of complete deletion (CD) mice. Credit: eLife (2022). DOI: 10.7554/eLife.72560 Using an in vivo model that mimics the genetic alteration of Williams-Beuren syndrome, researchers from the UPF’s Neuropharmacology Laboratory—NeuroPhar, in collaboration with several other universities, found alterations in the...
by Hunter Medical Research Institute Tumor response, PFS, and OS. A, Spider plot of tumor burden change of target lesions in reference to the baseline tumor burden in 18 patients with measurable tumor burden. RECIST/iRECIST, biopsies, and translational bloods were collected at week 9 after azacitidine/carboplatin and week 22 after six cycles of avelumab (indicated...
A new immunological treatment against hepatitis B and D viruses, both of which can cause liver cancer, shows promising results in animal models. Results from the treatment, which researchers at Karolinska Institutet are developing, have been published in the journal Gut. Chronic infections of the hepatitis B virus (HBV) and hepatitis D virus (HDV) are major...
by University of Cincinnati Credit: Pixabay/CC0 Public Domain Each year in the U.S., more than 500,000 people sustain tears in their meniscus, a piece of cartilage in the knee that cushions and stabilizes the joint. The tears often require invasive surgeries that frequently do not achieve the desired outcome. Researchers at the University of Cincinnati...
UNIVERSITY OF NEW SOUTH WALES People challenged with chronic back pain have been given hope with a new treatment that focuses on retraining how the back and the brain communicate, a randomised controlled trial run by researchers at UNSW Sydney and Neuroscience Research Australia (NeuRA) and several other Australian and European universities has shown. The...
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER CLEVELAND—Metabolic syndrome increases a person’s risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar. In a recent mouse-model study, published in Cell Metabolism, researchers at University Hospitals (UH), Harrington Discovery Institute at UH, and Case Western Reserve University have furthered...
