In today’s open access paper, the authors report on their investigation of the effects of nicotinamide mononucleotide (NMN) supplementation on the gut microbiome in mice. The gut microbiome changes with age, exhibiting a loss of helpful populations that produce metabolites necessary to health, and the growth in harmful populations that provoke chronic inflammation. Rejuvenating the aged gut microbiome via fecal microbiota transplantation from a...
Tag: <span>nicotinamide</span>
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Aging-US: Nicotinamide mononucleotide in degenerative model of retinal detachment
IMPACT JOURNALS LLC CREDIT: CORRESPONDENCE TO: DEMETRIOS G. VAVVAS IMAGE: Protective effects of delayed NMN administration to retinal detachment (RD). (A) A flow chart for the in vivo experiments. (B-E) Delayed NMN administration still have protective effect to outer nuclear layer (ONL) thickness 7 days post RD. N = 3 to 4 eyes per group....
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Brain study finds a molecular “off” switch for nicotine craving
Like any addiction, nicotine dependence warps the brain in elaborate ways—which is why treating it tends not to be as simple as mastering one’s willpower. Even after trying every technique in the toolbox—the support of friends, family, and a great therapist; nicotine patches; prescription drugs—many smokers will sooner or later experience a craving of overpowering...
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Researchers find that nicotinamide may help treat fibrotic eye diseases and mitigate vision loss
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE Nicotinamide, a form of vitamin B3, can inhibit aggressive cell transformations during wound healing and may be key to the development of therapies to treat fibrotic eye diseases that impair vision, according to a new Mount Sinai study published on Thursday, April 2, in Stem...