University of Science and Technology of China image: Schematics of GPR34 regulating ILC1 function during tumor progression and suppression. Credit: Image by Prof. ZHOU’s team A research team led by Prof. ZHOU Rongbin from the University of Science and Technology of China (USTC) discovered the mechanism by which lysophosphatidylserine (LysoPS) inhibits the anti-tumor activity of...
Tag: <span>NK cells</span>
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Natural killer cells that live in the lungs can rapidly respond to a sugar rush, making them especially effective
CD56brightCD16− NK cells in human BALF have a tissue-resident phenotype and distinct metabolic profile. Credit: Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2412489121 Trinity College Dublin researchers based at St James’s Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown but crucial natural killer (NK) immune cell resident in...
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NK cells with bispecific antibody show activity against lymphoma cells
UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER IMAGE: KATY REZVANI, M.D., PH.D. CREDIT: MD ANDERSON HOUSTON – Cytokine-activated natural killer (NK) cells derived from donated umbilical cord blood, combined with an investigational bispecific antibody targeting CD16a and CD30 known as AFM13, displayed potent anti-tumor activity against CD30+ lymphoma cells, according to a new preclinical...