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LP-284 targets non-Hodgkin’s lymphoma and DNA damage repair deficiency
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LP-284 targets non-Hodgkin’s lymphoma and DNA damage repair deficiency

by Impact Journals LLC Figure 6: LP-284 is selectively lethal in cells with TC-NER deficiency. Credit: Oncotarget (2023). DOI: 10.18632/oncotarget.28454 A new research paper titled “LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin’s lymphoma models and in cells deficient in DNA damage repair” has been published in Oncotarget. Despite advances in therapies treating non-Hodgkin’s lymphoma (NHL),...