by University of Massachusetts Amherst Fig. 1: The intracellular lifestyle of Salmonella is controlled by flhDC. a The design goals were to genetically engineer a bacterial vehicle that (1) synthesizes a protein drug (yellow/purple), (2) actively invades into cancer cells, and (3) releases drug, which escapes Salmonella vacuoles (SCVs, red). b, c Ninety-six hours after intratumoral...