by University of Helsinki Fig. 1: Generating proliferative induced hepatocytes using defined transcription factors and oncogenic drivers. A Schematic outline of the cell transformation assay for making lineage-specific cancer by lentiviral expression of three lineage-specific TFs to convert HFs to induced hepatocytes (iHep) and defined oncogenic drivers to transform iHeps to proliferating and tumorigenic cells. B...
Tag: <span>normal cells</span>
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Researchers discover two key events that turn normal cells into cancer
by Perelman School of Medicine at the University of Pennsylvania More than 100 cancer types can arise all over the body, but two universal metabolic pathways may tie them all together, researchers from the Perelman School of Medicine at the University of Pennsylvania report in a new study published today online in Cell Metabolism. Researchers have long believed all cancers are...