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Researchers discover novel mediator of once-mysterious chronic itch
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Researchers discover novel mediator of once-mysterious chronic itch

by  Johns Hopkins University School of Medicine Johns Hopkins Medicine researchers have shown that a subset of T lymphocytes (immune cells seen at upper left) known as Th22 cells secrete a protein, interleukin-22 (center), that increases chemical signaling throughout the skin. This mediates inflammation that can lead to prurigo nodularis, also known as chronic itch (clinical...