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Novel PET imaging agent detects earliest signs of Alzheimer’s disease
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Novel PET imaging agent detects earliest signs of Alzheimer’s disease

by Society of Nuclear Medicine Graphical abstract. 18F-SMBT-1 PET studies showed that Ab+ Alzheimer’s disease (AD) patients, but most importantly, Ab+ controls (CN) have significantly higher regional 18F-SMBT-1 binding than Ab- CN, with 18F-SMBT-1 retention highly associated with Ab burden. These findings suggest that increased 18F-SMBT-1 binding is detectable at the preclinical stages of Ab accumulation. Credit: Journal of Nuclear...