Tag: <span>Nuclear neurology</span>

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Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus
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Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains, Johns Hopkins University (Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore protein Pom121 than healthy brain cells, which leads to disrupted transport routes and ultimately cell death. Credit: Alyssa Coyne Researchers have long sought to explain...

Newly Synthesized Fungal Compound Can Switch on a Self-destruct Button for Cancer
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Newly Synthesized Fungal Compound Can Switch on a Self-destruct Button for Cancer

Leading organic chemists synthesize fungal molecule capable of reactivating the self-destruct gene in aggressive cancer cells. Cancers cells use a special technique to propagate; they delete their “programmed death” gene through mutation, “forget” to die when their lifetime is over and continue to grow instead. A research team from Tokyo University of Science has developed...

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From Alzheimer’s to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases

Image of glucose metabolism PET overlaid on CT in an Alzheimer’s patient with mild dementia. Green arrow points to regional hypometabolism in the medial parietal lobe, (which processes biographical information and memory),a proposed biomarker for Alzheimer’s. UB researcher with database of 16,000 brain scans proposes that powerful imaging can transform neurology as it did cardiology...