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Study shows bariatric surgery outperforms GLP-1 diabetes drugs for kidney protection
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Study shows bariatric surgery outperforms GLP-1 diabetes drugs for kidney protection

September 20, 2024 by Cleveland Clinic Credit: Pixabay/CC0 Public DomainA Cleveland Clinic study showed that in patients with type 2 diabetes, obesity, and chronic kidney disease, bariatric surgery was associated with a significant decrease in the progression of chronic kidney disease compared to those who received GLP-1 diabetes medications. The paper was published in Annals...

Cellular sludge around hunger neurons linked to worsening diabetes and obesity
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Cellular sludge around hunger neurons linked to worsening diabetes and obesity

By Pooja Toshniwal PahariaReviewed by Danielle Ellis, B.Sc. Researchers uncover how the buildup of extracellular matrix proteins and sugars prevents insulin from reaching hunger-regulating neurons, leading to disrupted metabolism and increased risk of obesity. Study: Pathogenic hypothalamic extracellular matrix promotes metabolic disease. Image Credit: Love Employee/Shutterstock.comIn a recent study published in Nature, researchers reveal a...

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‘Remarkable’ Weight Loss Seen With Novel Oral Combination That Is Safe and Tolerable in Phase 1 Study

Medscape Medical News > Conference News > EASD 2024 Becky McCall September 12, 2024 MADRID — Amycretin, a dual pathway, oral weight loss drug, led to up to 13% body weight loss in participants with overweight or obesity according to phase 1, first-in-human study data presented at the European Association for the Study of Diabetes...

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Breaking the link between obesity and atrial fibrillation with a new cellular target

News Release 4-Sep-2024 Peer-Reviewed PublicationUniversity of Illinois Chicago A cellular link between obesity and atrial fibrillation — a heart condition that afflicts over 33 million people worldwide — presents a promising target for new therapies, researchers from the University of Illinois Chicago report. Obesity is among the leading causes of atrial fibrillation, an irregular heart...

Diabetes and obesity can cause liver failure—but few people know their risk of developing liver disease
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Diabetes and obesity can cause liver failure—but few people know their risk of developing liver disease

JULY 22, 2024 by Madona Azar, The Conversation Credit: Unsplash/CC0 Public DomainLiver disease is frighteningly common worldwide. Metabolic dysfunction-associated steatotic liver disease, or MASLD, is an umbrella term describing conditions related to a buildup of fat in the liver. Formerly known as nonalcoholic fatty liver disease, this condition affects 1 in 4 people worldwide. Among...

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Should South Park: The End of Obesity Be Required Viewing in Medical School?

Medscape Diabetes & Endocrinology > Expounding on ObesityCOMMENTARY Yoni Freedhoff, MD DISCLOSURES | June 28, 2024 Yes, there’s still much to find offensive, but South Park: The End of Obesity, in just 51 minutes, does more to explain some of obesity’s realities, its pharmacotherapy, and weight bias than the mainstream media has done perhaps ever....

India left waiting another year for Wegovy
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India left waiting another year for Wegovy

Novo Nordisk is ”very enagaged” in India, the CFO says, but the weight-loss drug will not be launched there until 2025. Photo: Tom Little BY CHRISTIAN BUNDGAARD28 May 2024at 09:50 People with obesity in India will have to wait to get access to Novo Nordisk’s big seller Wegovy, according to the local Indian media Business...

Weight Loss Drug Tested in Mice May Be More Effective Than Existing Medicines
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Weight Loss Drug Tested in Mice May Be More Effective Than Existing Medicines

Promising new therapy for obesity that leads to greater weight loss in mice than existing medications. NewsPublished: May 17, 2024 | Original story from the University of Copenhagen Credit: Diana Polekhina / Unsplash. “I consider the drugs available on the marked today as the first generation of weight-loss drugs. Now we have developed a new...