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Methionine restriction observed to reverse old-age obesity in mice
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Methionine restriction observed to reverse old-age obesity in mice

by Impact Journals LLC Blood methionine level at day 15 (A) and day 29 (B). Credit: 2023 Kubota et al Obesity increases with aging. Methionine restriction affects lipid metabolism and can prevent obesity in mice. In a new study published in the journal Aging, researchers from AntiCancer Inc., University of California San Diego and Showa University School of...

Glucose-dependent insulinotropic polypeptide prevents diet-induced obesity in mice
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Glucose-dependent insulinotropic polypeptide prevents diet-induced obesity in mice

GIFU UNIVERSITY IMAGE: THE MECHANISM OF GIPFA-085-MEDIATED INHIBITION OF DIET-INDUCED OBESITY IN MICE SHOWS THAT GIPS HAVE THERAPEUTIC POTENTIAL IN TREATING OBESITY AND DIABETES CREDIT: TOSHIHIKO YADA FROM GIFU UNIVERSITY The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese...

CNIO researchers discover that a drug already in use in humans corrects obesity in mice
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CNIO researchers discover that a drug already in use in humans corrects obesity in mice

CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) IMAGE: VISUALIZATION OF ADIPOCYTES FROM AN OBESE MOUSE (LEFT) AND FROM A LEAN MOUSE TREATED WITH DIGOXIN (RIGHT), SHOWING A BETTER RESPONSE TO NUTRIENT EXCESS AND BURNING OF FAT. CREDIT: CNIO It has long been known that obesity is an inflammatory disease, i.e. a chronic defensive reaction of the...