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‘Olive oil’ drug shows early promise for some brain cancer patients
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‘Olive oil’ drug shows early promise for some brain cancer patients

by Institute of Cancer Research Mechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important lipid metabolism enzymes. (2) Among other structural effects on the lipid bilayer, these changes in lipid composition regulate the raft-to-nonraft lipid balance, which causes translocation of numerous...