MAYO CLINIC ROCHESTER, Minn. — Surgical patients receiving the opioid tramadol have a somewhat higher risk of prolongeduse than those receiving other common opioids, new Mayo Clinic research finds. However, the Drug Enforcement Administration (DEA) classifies tramadol as a Schedule IV controlled substance, meaning it’s considered to have a lower risk of addiction and abuse thanSchedule II opioids, such as oxycodone and hydrocodone. The study was published...
Tag: <span>opioids</span>
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Opioids don’t have to be addictive – the new versions will treat pain without triggering pleasure
The problem with opioids is that they kill pain – and people. In the past three years, more than 125,000 persons died from an opioid overdose – an average of 115 people per day – exceeding the number killed in car accidents and from gunshots during the same period. America desperately needs safer analgesics. To create them, biochemists...
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Chronic back pain stem cell treatment could cut need for opioids
Lower back pain affects around 28 million people in the US plainpicture A stem cell treatment could finally bring relief to millions of people with chronic lower back pain. If it works, the injection could become a crucial tool for curbing the opioid epidemic currently killing thousands in the US. Overdoses from prescription opioids have quadrupled since 1999,...
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Specialized compound could lead to chronic pain relief without the use of opioids
Purdue researchers have discovered a compound that could lead to the treatment of chronic pain without the need for patients to rely on opioids. A team led by Val Watts, associate head and professor of medicinal chemistry and molecular pharmacology in Purdue’s College of Pharmacy, said the compound shows unparalleled selectivity in inhibiting the adenylyl cyclase 1...
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