by Vanderbilt University Medical Center Identification of a unique heterozygous mutation in the IRF4 gene in seven CID patients. Credit: Science Immunology (2023). DOI: 10.1126/sciimmunol.ade7953 An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, Ph.D., has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia....
Tag: <span>opportunistic infections</span>
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New approach to treat inflammatory disorders while preserving protection against opportunistic infections
Researchers at Case Western Reserve University have discovered a new technique to control inflammatory disorders that also maintains a patient’s ability to fight off infections. Principal investigator Carlos Subauste, professor of medicine and pathology at the Case Western Reserve School of Medicine, and his team have identified the interaction of particular proteins as a therapeutic target...