News Release 26-Sep-2024 Discovery could pave the way for personalized therapeutics to treat the chronic inflammatory bowel disease Peer-Reviewed PublicationUniversity of California – San Diego Histology images of patient-derived organoids: healthy (left), Crohn’s disease SF2CD subtype (middle) and Crohn’s disease IDICD (right). Image courtesy of Pradipta Ghosh. Credit: UC San Diego Health Sciences Crohn’s disease...
Tag: <span>Organoids</span>
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Organoids reveal similarities between myotonic dystrophy type 1 and Rett syndrome
by University of California – San Diego Credit: Pixabay/CC0 Public Domain Myotonic dystrophy type 1 (DM1) is the most common form of muscular dystrophy, characterized by progressive muscle wasting and weakness and caused by abnormally repetitive DNA segments that are transcribed into toxic molecules of RNA. Instead of ferrying a gene’s instructions for translation into proteins,...
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Organoids reveal the tipping point when kidney damage turns irreversible
By Elizabeth Cooney March 2, 2022 Reprints Kidney organoids with markers of nephrons (purple, light blue, green) and stroma (red and yellow). Researchers used the miniature models to study when kidney damage turns irreversible.N. GUPTA, ET AL., SCIENCE TRANSLATIONAL MEDICINE Chronic kidney disease is a serious medical problem that changes the lives of about 13%...