TOKYO METROPOLITAN UNIVERSITY IMAGE: HYPEROSMOTIC STRESS LEADS TO A REORGANIZATION OF ACTIN STRUCTURE IN TUBULAR EPITHELIAL CELLS, WITH ELEVATED INCORPORATION OF ALPHA-SMA AND REORGANIZATION OF FOCAL ADHESIONS. THIS LEADS TO EMT, AS EVIDENCED BY A DECREASE IN E-CADHERIN EXPRESSION. (BOTTOM) FLUORESCENCE SIGNAL SHOWING THE DECREASE IN E-CADHERIN (LEFT) AND INCREASE IN ALPHA-SMA (RIGHT) IN KIDNEY...
