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Biomedical engineers demonstrate potential for the first clinically successful osteoarthritis drug
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Biomedical engineers demonstrate potential for the first clinically successful osteoarthritis drug

by Marissa Shapiro,  Vanderbilt University Blocking MMP-13 reduces structural changes to mechanically injured joints. Top: Histological images of trichrome-stained sections showing that blocking MMP-13 protects cartilage structure and composition. Bottom: Micro-computed tomography imaging of mineralized tissues indicate that MMP-13 inhibition reduces unnatural mineralization and bone spurs in the mechanically injured joints. Red arrows and # symbols...