A new Japanese study finds that among non-depressed older adults with osteoarthritis knee pain, nearly 12 percent will go on to develop symptoms of depression within two years. Participants at greatest risk for depression include those who experience knee pain while lying in bed at night, while putting on socks, or while getting in or out of a car....
Tag: <span>Osteoarthritis</span>
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Cartilage degeneration algorithm predicts progression of osteoarthritis
A novel cartilage degeneration algorithm can predict the progression of osteoarthritis in individual patients, according to new research from the University of Eastern Finland. The new algorithm could greatly facilitate clinical decision-making in the treatment of osteoarthritis. Osteoarthritis (OA) is a joint disease that deteriorates the articular cartilage. The most important risk factors are ageing and...
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Osteoarthritis: Could this algae extract lead to a cure?
Osteoarthritis is a joint disease, characterized by the breakdown of the joint cartilage. This condition has, so far, been considered incurable, and treatments are only symptomatic. However, new research points to a substance extracted from brown algae as holding the potential to cure osteoarthritis. Modified chemical extracts from the Laminaria hyperborea algae (shown here) have...
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Fluid in the knee holds clues for why osteoarthritis is more common in females
Researchers have more evidence that males and females are different, this time in the fluid that helps protect the cartilage in their knee joints. They have found in the synovial fluid of this joint, clear differences in the messages cells are sending and receiving via tiny pieces of RNA, called microRNA, in males and females...
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Removing Old Cells Could Prove Effective In Stopping Osteoarthritis
The signs of aging can be a literal pain, especially for those with sedentary lifestyles who are more prone to experiencing joint and muscle pains. While professionals recommend having an active lifestyle to lower the risk of osteoarthritis development, researchers look inside our own bodies to determine how to fight the natural course of aging. A previous study found...
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A steroid jab in the bottom could ease hip pain caused by osteoarthritis for up to 12 weeks
The steroid injection was trialled by researchers in the Netherlands Relief period matched that of steroid injections directly into the affected joint The buttock jab is much less painful and can be administered by GPs An estimated nine million people in Britain have some degree of osteoarthritis A single steroid injection to the buttocks could...
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Clearing out old cells could extend joint health, stop osteoarthritis
In a preclinical study in mice and human cells, researchers report that selectively removing old or ‘senescent’ cells from joints could stop and even reverse the progression of osteoarthritis. The findings, published April 24 in Nature Medicine, support growing evidence that senescent cells contribute to age-related diseases and demonstrate that using drug therapies to remove them...
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Impact of total knee replacement practice: cost effectiveness analysis of data from the Osteoarthritis Initiative
Abstract Objectives To evaluate the impact of total knee replacement on quality of life in people with knee osteoarthritis and to estimate associated differences in lifetime costs and quality adjusted life years (QALYs) according to use by level of symptoms. Design Marginal structural modeling and cost effectiveness analysis based on lifetime predictions for total knee...