by Shinshu University In a new study, researchers from Japan reveal that iSN40 suppresses osteoclast differentiation and bone matrix resorption, offering a potential therapeutic approach for osteoporosis by restoring the balance between bone formation and resorption. Credit: Dr. Tomohide Takaya, Shinshu University, Japan Osteoporosis, characterized by an imbalance in bone remodeling, is a growing health concern...
Tag: <span>Osteoporosis</span>
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Genetic variants in melatonin receptor linked to idiopathic osteoporosis
by Justin Jackson , Medical Xpress Credit: cottonbro studio from Pexels Columbia University Medical Center researchers have identified specific variants in a melatonin receptor gene that impair bone turnover, leading to significant reductions in bone density and increased risk of fractures, particularly in Ashkenazi Jewish individuals. Osteoporosis is a common bone disorder characterized by low...
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Protein blocking bone development could hold clues for future osteoporosis treatment
Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation. In their paper published in Communications Biology 11 October 2024, a team of researchers led by Dr. Amy Naylor and Professor Roy Bicknell along with their team including Dr. Georgiana Neag...
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New gene linked to osteoporosis identified
JULY 1, 2024 by Osaka University Molecular mechanism of senescence induced by osteoblast MEN1 deficiency SASP: senescence-associated secretory phenotype. Credit: Aging Cell (2024). DOI: 10.1111/acel.14254Osteoporosis—weakening of the bones with age—affects millions worldwide, and this figure is increasing annually as the global population ages. It is associated with the aging, or “senescence,” of bone cells, but...
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USPSTF recommends osteoporosis screening for women aged 65 years and older
JUNE 11, 2024 by Elana Gotkine The U.S. Preventive Services Task Force (USPSTF) recommends screening for osteoporosis for women aged 65 years and older and for postmenopausal women younger than 65 years with one or more risk factors. These recommendations form the basis of a draft recommendation statement published online June 11. Researchers reviewed the...
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HKU scientists unveil significant discovery with potential impact on obesity and osteoporosis treatments
THE UNIVERSITY OF HONG KONG SECRETIN SIGNALING IN THE VENTROMEDIAL HYPOTHALAMUS REGULATES SKELETAL AND METABOLIC HOMEOSTASIS. IMAGE ADAPTED FROM RESPECTIVE PAPER IN NATURE COMMUNICATIONS (2024) view moreCREDIT: THE UNIVERSITY OF HONG KONG A team of researchers from The University of Hong Kong (HKU) has made a significant breakthrough in understanding how energy metabolism and bone...
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Compounds in female ginseng could lead to new osteoporosis treatments
by American Chemical Society Credit: Unsplash/CC0 Public Domain With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis. Although there are effective drugs for treating this metabolic bone disease, they can be expensive and have side effects, limiting their availability to some people.In the search for alternative drug candidates, researchers reporting in...
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Women with osteoporosis want to know their fracture risk
by Lori Solomon Most women with osteoporosis want to know their fracture risk, but only half have received this information from health care providers, according to a study published online Nov. 13 in Osteoporosis International. Charlotte Beaudart, Ph.D., from Maastricht University in the Netherlands, and colleagues used data from the Risk Communication in Osteoporosis study...
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DOES GUT BACTERIA CAUSE OSTEOPOROSIS?
POSTED BY ANDREW YAWN-TULANE “This study established that the gut microbiome is important for our bone health and getting a healthy microbiome composition is important,” Hong-Wen Deng says. “Now that we’ve identified a target in B. vulgatus, we want to lower its abundance.” One of the most common forms of gut bacteria may be to blame...
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Bone Degradation Measure Can Sway Osteoporosis Diagnosis
Jake Remaly October 12, 2023 Assessing a key aspect of bone architecture, for which clinicians can now be reimbursed under Medicare, can significantly improve the ability to predict a patient’s risk for bone fracture. Although bone mineral density (BMD) is traditionally used to identify patients with osteoporosis or low bone mass, some physicians have begun incorporating the...