by University of Sheffield Credit: Pixabay/CC0 Public Domain Osteoporosis in men is often overlooked by health care professionals, a study in The Lancet Diabetes and Endocrinology from the University of Sheffield has found. Researchers say raising awareness of the condition in men is desperately needed to help improve outcomes for patients. Osteoporosis is a condition where the...
Tag: <span>Osteoporosis</span>
Targeting Cellular Senescence as a Basis for Treating Osteoporosis
Senescent cells accumulate with age, causing tissue dysfunction throughout the body via their inflammatory secretions. One of those dysfunctions is the age-related imbalance in bone remodeling, favoring the osteoclasts that break down bone tissue at the expense of the osteoblasts that rebuild it. The result is osteoporosis, the characteristic loss of bone mass and resilience that...
Simple clinical tool to diagnose spinal fractures in people with osteoporosis
by University of Bristol Credit: Pixabay/CC0 Public Domain Only 1 in 3 patients are diagnosed with broken bones in the back due to osteoporosis. One reason is that medical staff find it difficult to know who should have a back X-ray. To help address this important diagnostic care gap, academics at the University of Bristol...
Men with high levels of body fat may be at risk for osteoporosis
by The Endocrine Society Men with high levels of body fat have lower bone density and may be more likely to break a bone than those with normal levels of body fat, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Most studies have shown positive or neutral effects of...
What is the difference between osteopenia and osteoporosis?
Bone mass and bone mineral density both decrease as people age. Osteopenia is a condition where people’s bone density is lower than is usual for their age. Osteoporosis is a more severe case of bone loss that weakens the bones and makes them more likely to fracture. Bone mass and bone mineral density measure the amount of...
How to manage osteoporosis in hematologic stem cell transplant recipients
INTERNATIONAL OSTEOPOROSIS FOUNDATION Impaired bone health is among the most significant long-term consequences of hematopoietic stem cell transplantation (HSCT), a common therapy for patients with malignant and non-malignant haematological diseases. To address this serious problem, the International Osteoporosis Foundation (IOF) expert Working Group on Cancer and Bone Disease has published a new Executive Summary of its authoritative...
Primary ovarian insufficiency associated with increased risk of osteoporosis
THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS) CLEVELAND, Ohio (March 3, 2021)–The loss of estrogen after menopause is associated with rapid bone loss. A new study compared the bone health outcomes in women with primary ovarian insufficiency (POI) and early menopause with women who experienced menopause at the standard age to confirm the association between POI...
Discovery of ‘adolescent’ skeletal stem cells might someday help prevent osteoporosis
Credit: AlphaMed Press Durham, NC – A new study reported in STEM CELLS reveals a unique population of skeletal stem cells (SSCs) that function during the transitional period between rapid bone growth and bone maintenance. This discovery provides an opportunity to determine whether alterations in the SSCs’ pattern might affect bone formation, as well as helps us...
New drug form may help treat osteoporosis, calcium-related disorders
by Purdue University Elizabeth Topp, a Purdue professor of physical and industrial pharmacy, helped develop a stabilized form of human calcitonin, which is a peptide drug already used for people with osteoporosis. Credit: Chris Adam/Purdue University A novel form of a drug used to treat osteoporosis that comes with the potential for fewer side effects may...
Potential Cellular Target for Eliminating Bone Breakdown in Osteoporosis Found
New research has discovered a cell type that governs the way bones form and maintains themselves, opening up a potential target for future therapies for bone disorders like osteoporosis. Led by faculty from the Perelman School of Medicine at the University of Pennsylvania, a rodent study showed that bone marrow adipogenic lineage precursors (MALPs) play a distinct...