Vertebroplasty (surgery to repair spinal fractures) is no more effective for pain relief than a sham (placebo) procedure in older patients with osteoporosis, finds a trial published by The BMJ today. The researchers say their results “do not support vertebroplasty as standard pain treatment in patients with osteoporotic vertebral fractures.” Osteoporosis is a disease in which bones become weak and more...
Tag: <span>Osteoporosis</span>
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ASBMR: Romosozumab reduces fracture rate in osteoporosis
(HealthDay)—Romosozumab treatment followed by alendronate is linked to reduced risk of fractures versus alendronate alone for postmenopausal women with osteoporosis, according to a study published online Sept. 11 in the New England Journal of Medicine. The research was published to coincide with the annual meeting of the American Society for Bone and Mineral Research, held from...
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Largest ever genetic study marks likely osteoporosis treatment target
Scientists are homing in on a potential treatment for osteoporosis, after performing the largest ever genetic study of the common age-related bone-thinning disease. Researchers from The University of Queensland and McGill University in Canada led the study, identifying 153 new gene variants associated with the loss of bone mineral density, which often result in fractures. UQ Diamantina Institute researchers Dr John Kemp...
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Drugs used to treat osteoporosis could have the opposite effect and make you more prone to fractures, study finds
Taking biphosphonates for more than five years alters the composition of bone Older women were found to be most at risk from taking the pills, experts said Such drugs, taken by millions worldwide, include Fosamax, Boniva and Reclast Drugs used to strengthen bones can actually have the opposite effect, scientists have warned. Taking biphosphonates for...
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Benefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease: A Systematic Review and Meta-analysis
Abstract Background: Complications of chronic kidney disease (CKD) include weak bones and increased fracture risk. Purpose: To review the benefits and harms of osteoporosis medications (bisphosphonates, teriparatide, raloxifene, and denosumab) compared with placebo, usual care, or active control in terms of bone mineral density (BMD), fractures, and safety in patients with CKD. Data Sources: PubMed...
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Could new bone-forming growth factor reverse osteoporosis?
Scientists at the Children’s Medical Center Research Institute at UT Southwestern in Dallas, TX, have uncovered a new bone-forming growth factor that may reverse the bone loss associated with osteoporosis. They say that this discovery has implications for regenerative medicine. Osteolectin has been shown to promote bone growth in postmenopausal mice. Osteoporosis develops over several...
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New Stem Cell Therapy Could Help Treat Osteoporosis and Restore Bones
IN BRIEF Four percent of all men over the age of fifty, and sixteen percent of women of the same age, suffer from osteoporosis in the United States. Researchers from University College London have discovered that stem cells found in human amniotic fluid could be used in a treatment to strengthen brittle bones. ASTRONAUT BONES...