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New research supports sofosbuvir in combination with other antivirals for COVID-19
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New research supports sofosbuvir in combination with other antivirals for COVID-19

by  Columbia University School of Engineering and Applied Science This figure shows that there is substantially more cleavage of Remdesivir-RNA (g, h, i) than Sofosbuvir-RNA (a, b, c) by SARS-CoV-2 exonuclease. It is also apparent that Remdesivir-RNA (g, h, i) is cleaved by the exonuclease more rapidly than RNA extended with UMP (d, e, f). The...