by University of Cambridge These images, from a small-scale unpublished study in human ovarian cancer patients, were created using a technique called hyperpolarized carbon-13 imaging that allows doctors to distinguish between different subtypes of ovarian cancer, to reveal their sensitivities to treatment. The scientists observed different rates of pyruvate conversion into lactate in different tumor deposits,...
Tag: <span>Ovarian Cancer</span>
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In situ tumor vaccine with optimized nanoadjuvants and lymph node targeting capacity to treat ovarian cancer and metastases
News Release 25-Sep-2024 Peer-Reviewed PublicationCompuscript Ltd This new article publication from Acta Pharmaceutica Sinica B, discusses the use of in situ tumor vaccine with optimized nanoadjuvants and lymph node targeting capacity to treat ovarian cancer and metastases. Tumor vaccine, a promising modality of tumor immunotherapy, needs to go through the process of tumor antigen generation...
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New research shows promise for urine-based test to detect ovarian cancer
Biophysical SocietyNew research by Joseph Reiner and colleagues at Virginia Commonwealth University shows promise for a urine-based test for ovarian cancer. Reiner will present their research at the 68th Biophysical Society Annual Meeting, to be held February 10 – 14, 2024 in Philadelphia, Pennsylvania. Previous research showed that there are thousands of small molecules, called...
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Researchers reveal mechanism of protection against breast and ovarian cancer
THE FRANCIS CRICK INSTITUTE In a new paper published today in Nature, researchers at the Francis Crick Institute have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer. Every time a cell replicates, mistakes can happen in the form of mutations, but specialised proteins exist to repair...
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Simple low-dose aspirin may boost ovarian cancer survival
by QIMR Berghofer Credit: QIMR New QIMR Berghofer research has found that low-dose aspirin may improve ovarian cancer survival. The study followed more than 900 Australian women newly-diagnosed with ovarian cancer, and asked them how often they used nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin. Lead researcher Dr. Azam Majidi said the women who reported taking NSAIDs at least four...
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New immunotherapy holds promise for ovarian cancer
by Karolinska Institutet Intermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) and mucinous epithelium that pseudo-stratifies (left – diagnostic of a LMP tumour). Epithelium in a frond-like architecture is seen at the top of image. Credit: Nephron /Wikipedia. CC BY-SA 3.0 CAR...
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Loyalty card data could help to identify ovarian cancer symptoms sooner
by Lancaster University The study of almost 300 women found that pain and indigestion medication purchases were higher in women who were subsequently diagnosed with ovarian cancer, compared to women who did not have ovarian cancer. Credit: Lancaster University Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier according to...
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Researchers link ovarian cancer to bacteria colonization in microbiome
by Susan Murphy, Mayo Clinic β-diversities measures were compared. For β-diversity, Bray–Curtis (BC), unweighted, and weighted, UniFrac distance metrics were reported. The most significant metric is shown in each ordination plot. (A–D) Bacterial community β-diversity between OC patients with sensitive vs other (resistant/refractory) tumor response. Fallopian tube, (A) β-diversity: sensitive vs other (p = 0.003). Ovaries, (B)...
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Ovarian cancer detection takes a step forward, thanks to Wilmot
UNIVERSITY OF ROCHESTER MEDICAL CENTER A new type of technology can capture stray ovarian cancer cells from a simple blood test and successfully predict cancer in people who have a lesion or cyst in the pelvic region, according to a new study by a Wilmot Cancer Institute physician/scientist. Nearly 200 local people participated in the study, which...
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Epigenetic ‘priming’ boosts ovarian cancer immunotherapy
by Will Doss, Northwestern University Graphical abstract. Credit: Journal of Clinical Investigation (2022). DOI: 10.1172/JCI158800 An epigenetic inhibitor can boost immune system activity in patients with ovarian cancer, making them more suitable for treatment with immunotherapy, according to a Northwestern Medicine study published in the Journal of Clinical Investigation. This could be one strategy to aid immunotherapy in...