UNIVERSITÄT LEIPZIG IMAGE: OXIDISED MODEL MEMBRANES HAVE DIFFERENT EFFECTS ON PEPTIDE FIBRIL FORMATION, DRIVEN BY MEMBRANE SURFACE ATTRACTION, PEPTIDE CHARGE AND PEPTIDE STRUCTURAL PROPERTIES. CREDIT: LEIPZIG UNIVERSITY The researchers wanted to better understand how cell membranes in the body influence the structure of peptides – these are molecules made up of amino acids – and their aggregation....
Tag: <span>oxidative stress</span>
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Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity
by Tokyo University of Science Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of Science Acrylamide is a toxic chemical compound that affects the nervous system. It is widely used in industries such as paper production, plastics, and wastewater management, and is also a byproduct of commonly-used food processing methods,...
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Full-genome CRISPR screen reveals surprising ways neurons survive oxidative stress
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO IMAGE: SUPER-RESOLUTION MICROSCOPY OF A NEURON SHOWS THE ACCUMULATION OF LIPIDS WITHIN LYSOSOMES THAT OCCURS WHEN THE GENE FOR PROSAPOSIN IS SUPPRESSED. CREDIT: UCSF When a single gene in a cell is turned on or off, its resulting presence or absence can affect the function and survival of the...