New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair. The findings could improve our understanding of the processes used by cells to repair tissues, and be used to identify interventions that could accelerate and improve wound repair. Epithelial tissues are the...
Tag: <span>p53 Protein</span>
P53 protein plays a key role in tissue repair, study finds
by University of Bristol Once the collective migration of cells has closed the breach, the damaged leader cells need to be cleared from the tissue. When the leaders (blue nuclei) cannot be eliminated by their neighbours (green nuclei) their permanence in the epithelium compromises its regular architecture. Credit: University of Bristol New research led by...
Researchers determine how the p53 protein can lead cancer cells to their death
by Università di Trento There is an ongoing battle between cancer cells and p53, the protein known as “the guardian of the genome,” and a study conducted at the University of Trento has identified a number of factors that influence the outcome of this battle and therefore the effectiveness of cancer treatments. Scientists explore two...
Opposite effect: Protein widely known to fight tumors also boosts cancer growth
Search for a description of “p53” and it becomes clear that this human protein is widely known for its cancer-fighting benefits, leading to its renown as “the guardian of the genome.” IMAGE: UC SAN DIEGO RESEARCHERS FOUND THAT THE PUMA PROTEIN WORKS INSIDE THE CELL’S MITOCHONDRIA TO SWITCH ENERGY PRODUCTION PROCESSES AND STIMULATE CANCER GROWTH.view...