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Study identifies new mechanisms that boost p53 signaling and tumor suppression
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Study identifies new mechanisms that boost p53 signaling and tumor suppression

by Ludwig Cancer Research Graphical abstract. Credit: Molecular Cell (2022). DOI: 10.1016/j.molcel.2022.04.010 A team led by Ludwig Stanford’s Laura Attardi explored novel mechanisms by which the p53 protein, often called the guardian of the genome, regulates gene expression by looking for novel proteins that interact with the versatile tumor suppressor in response to cellular stressors. The researchers...