by University of Arizona The structure of compound 194 (yellow sticks) overlaid on an electrophysiology trace showing reduced sodium currents (yellow vs. black lines) from cells that are treated with compound 194. The structure illustrates the predicted interaction of CRMP2 (pink, PDB 2GSE) with the Nav1.7 channel (cyan, PDB 6J8G). Credit: University of Arizona Health...
by University at Buffalo Credit: Unsplash/CC0 Public Domain An investigation into the origins of the sensation of pain has led to the development of a novel and durable treatment for inflammatory pain that could be a promising alternative to opioids. The preclinical research was conducted by neuroscientists and pharmacologists, all in the Jacobs School of Medicine...
UNIVERSITY OF ARIZONA HEALTH SCIENCES SARS-CoV-2, the virus that causes COVID-19, can relieve pain, according to a new study by University of Arizona Health Sciences researchers. The finding may explain why nearly half of people who get COVID-19 experience few or no symptoms, even though they are able to spread the disease, according to the...
Lower back problems are very common. They can cause a constant dull ache or a sudden sharp pain. Lower back pain has a variety of possible causes, which range from poor posture to underlying medical conditions. However, certain stretches may help by relieving pain and improving flexibility. In this article, we discuss the types of...
By Staff Reporter Tech Times Did you know that back pain was the major cause of disability on a global level? Over 50% of all working Americans face symptoms of back pain each year. This is the most common reason why they have to miss working days. While you’re still young and vibrant, you don’t see this...
Did you know that back pain was the major cause of disability on a global level? Over 50% of all working Americans face symptoms of back pain each year. This is the most common reason why they have to miss working days. While you’re still young and vibrant, you don’t see this as a serious health issue....
by American College of Rheumatology According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but did significantly reduce the progression of joint damage over placebo and seems...
Damian McNamara October 22, 2019 A novel, noninvasive, over-the-counter electromagnetic neuromodulation device (ActiPatch, BioElectronics Corp.) appears to deliver long-lasting relief in chronic pain patients. However, at least one pain expert has concerns about the study methodology and interpretation of the results. Results of a long-term prospective study that included 240 patients who had previously experienced chronic pain...
by Len Canter, Healthday Reporter (HealthDay)—Sore from a workout? You don’t have to reach for pain relief medicine when ice or heat will help. But when should you go cold and when should you go warm? Ice is the go-to therapy when an injury first happens. It can stop the swelling of a sprained ankle, for instance,...
Some cancers love bone. They thrive in its nutrient-rich environment while gnawing away at the very substrate that sustains them, all the while releasing inflammatory substances that cause pain—pain so severe that opioids often are prescribed to allay the agony. But opioids recently have been denounced for their addictive nature. This summer, the nation’s opioid...
