Peer-Reviewed Publication Xia & He Publishing Inc. image: (a) Potential mechanisms by which a disturbed gut microbiome contributes to cancer pathogenesis. (b) Proposed mechanisms by which FMT restores the gut microbiome and reestablishes microecosystem homeostasis. FMT, fecal microbiota transplantation; SCFA, short-chain fatty acids.view more Credit: Xiangyu Kong, Xiulin Hu, Congjia Ma Pancreatic ductal adenocarcinoma (PDAC) is...
Tag: <span>Pancreatic cancer</span>
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Innovative urine test could improve pancreatic cancer survival rates
By Vijay Kumar MalesuReviewed by Lily Ramsey, LLMNov 14 2024 Urinary miRNA-based assay shows high accuracy, potentially transforming pancreatic cancer screening. Study: A noninvasive urinary microRNA-based assay for the detection of pancreatic cancer from early to late stages: a case control study. Image Credit: Krakenimages.com/Shutterstock.com In a recent study published in the eClinicalMedicine, a group of researchers evaluated the effectiveness...
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Weight-loss surgery may lower risk of pancreatic cancer in people with obesity
Obesity and type 2 diabetes are risk factors for various malignancies, including pancreatic cancer, which has a high death rate. A new analysis in Diabetes/Metabolism Research and Reviews suggests that weight-loss surgery—also called metabolic-bariatric surgery—may lower the risk of developing pancreatic cancer in people with obesity, especially in those who also have type 2 diabetes. In the systematic review and meta-analysis,...
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New pancreatic cancer treatment proves effective in shrinking, clearing tumors
August 28, 2024 by University of Massachusetts Amherst Researchers at the University of Massachusetts Amherst and UMass Chan Medical School have demonstrated in mice a new method to combat pancreatic cancer. The study, published in Science Translational Medicine, outlines the synergistic effects of a novel nanoparticle drug-delivery system to activate an immune pathway in combination...
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Faster detection of pancreatic cancer
News Release 9-Aug-2024 Glycopeptide probes detect tumor-associated antibodies in blood samples Peer-Reviewed PublicationWiley Pancreatic cancer is one of the most lethal forms of cancer, primarily because it is usually diagnosed very late. Current markers are too insensitive and unspecific for early detection screenings. In the journal Angewandte Chemie, a research team has now introduced a...
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Detecting pancreatic cancer through changes in body composition and metabolism
July 30, 2024 by Marla Broadfoot, Ph.D., Mayo Clinic News Network Graphical abstract. Credit: Clinical Gastroenterology and Hepatology (2024). DOI: 10.1016/j.cgh.2024.03.038Pancreatic cancer is a formidable disease, often diagnosed too late for effective treatment. However, new research from Mayo Clinic represents a promising step toward identifying biological signals or biomarkers that may aid in early detection....
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A smart molecule beats the mutation behind most pancreatic cancer
by Levi Gadye, University of California, San Francisco Intrinsic reactivity and stability of G12Di-6 and 7. a, Stability in the presence of excess compounds (5 mM) bearing reactive functional groups. All data points represent individual biological replicates. Data are presented as mean ± SD (n = 2). b, Stability in 1X PBS at various pH. All data points represent individual biological...
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Age-related changes in fibroblast cells promote pancreatic cancer growth and spread
by Johns Hopkins University School of Medicine Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainOlder people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns...
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TEAM UNCOVERS A KEY ACTOR IN PANCREATIC CANCER’S SPREAD
POSTED BY ANDY FELL-UC DAVIS Researchers have identified a protein linked to metastasis in pancreatic cancer. Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed. Severe pancreatic cancer is associated with metastasis, and it is this spread of secondary tumors...
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Vaccine targeting KRAS in pancreatic and colorectal cancer shows promise
Peer-Reviewed Publication MEMORIAL SLOAN KETTERING CANCER CENTER MEMORIAL SLOAN KETTERING CANCER CENTER MEDICAL ONCOLOGIST EILEEN O’REILLY HELPED LEAD A CLINICAL TRIAL INVESTIGATING A READY-MADE VACCINE AS A TREATMENT FOR PANCREATIC AND COLORECTAL CANCERS WITH CERTAIN KRAS MUTATIONS.CREDIT: MEMORIAL SLOAN KETTERING A new vaccine shows encouraging early results as a potential off-the-shelf treatment for certain patients...