LONDON, ON – In a new study from Lawson Health Research Institute and Western University’s Schulich School of Medicine & Dentistry, researchers have found that mutation of a gene called ATRX may lead to increased risk of developing pancreatitis and pancreatic cancer in females. The study marks the first time a sex-specific genetic risk factor...
Tag: <span>Pancreatic cancer</span>
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Killer cell Immunotherapy offers potential cure for advanced pancreatic cancer
A new approach to treating pancreatic cancer using ‘educated killer cells’ has shown promise, according to a new study by UNSW medical researchers. Researchers from UNSW Sydney and the California Institute of Biomedical Research (CALIBR) have demonstrated the success of a new, cell-based immunotherapy for pancreatic cancer. The treatment led to mice being completely cancer-free,...
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Blocking digestive hormone may prevent diet-induced pancreatic cancer
Cholecystokinin pathways influence cancer progression and spread AMERICAN PHYSIOLOGICAL SOCIETY Rockville, Md. (Aug. 2, 2018)–A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking CCK may help prevent the spread of pancreatic tumors to other areas...
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Molecular ‘rabble-rouser’ fuels pancreatic cancer growth
A type of molecular ‘rabble-rouser’ that triggers pancreatic cancer to become aggressive and spread around the body has been identified by scientists. Aggressive pancreatic cancer cells. Credit: Imperial College London The team behind the early-stage research, led by Imperial College London and funded by Pancreatic Cancer UK, say the findings may open avenues for treatments that...
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Pancreatic cancer: Some blood pressure drugs put women at risk
New research suggests that certain blood pressure drugs may increase the risk of pancreatic cancer in postmenopausal women. pancreatic cancer, a new study suggests. Zhensheng Wang, a postdoctoral researcher at the Dan L. Duncan Comprehensive Cancer Center at Baylor College of Medicine in Houston, TX, along with his colleagues, set out to examine the effects...
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Gut bacteria determine speed of tumor growth in pancreatic cancer
The population of bacteria in the pancreas increases more than a thousand fold in patients with pancreatic cancer, and becomes dominated by species that prevent the immune system from attacking tumor cells. These are the findings of a study conducted in mice and in patients with pancreatic ductal adenocarcinoma (PDA), a form of cancer that...
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TGen testing whether ultrasound can help fight pancreatic cancer
SCOTTSDALE, AZ – In the battle against pancreatic cancer, a Phoenix-based organization will soon begin testing a new method that may enhance the effectiveness of current treatments. The Translational Genomics Research Institute, or TGen, will begin testing with ultrasound next week. The organization is working with a Norwegian biotech company, Phoenix Solutions. “It could…significantly improve...
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Researchers identify epigenetic orchestrator of pancreatic cancer cells
Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells’ chromatin. The study, which will be published December 11 in the Journal of Cell Biology, suggests that targeting this enzyme could make pancreatic cancer cells more vulnerable to existing therapies that currently have only...
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How inhibiting one protein could help to treat pancreatic cancer
Targeting an enzyme that makes pancreatic cancer cells more aggressive by silencing some of their genes could make the deadly disease less resistant to treatment. Could the findings of a new study help in the fight against pancreatic cancer? This was the conclusion of new research from Genentech, a biotechnology company in South San Francisco,...
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Pancreatic cancer is often deadly. But recent discoveries are starting to unravel its mysteries — and raise hope
Pancreatic cancer cellsANNE WESTON/WELLCOME IMAGES Pancreatic cancer is deadly: It’s difficult to detect and bedeviling to treat. Just 20 percent of patients survive a year after diagnosis. Less than 10 percent make it to the five-year mark. But recent discoveries — both in the lab and in patients — are raising hope. They’re still early stage....