by Rush University Medical Center Neutralization of p402 and p40 increases levels of IFN-γ in pancreatic cancer cells. Immunohistochemical analysis at 60× magnification of PANC-1 (A) and BxPC-3 cells (B) treated with p40 homodimer or p40 monomer were labeled with IFN-γ (red). DAPI was used to stain the nuclei. Cells positive for IFN-γ were counted and...
by University of Texas M. D. Anderson Cancer Center Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA vaccine has shown potential to prevent relapse of KRAS-mutated pancreatic and colorectal cancers for patients who had previously undergone surgery, according to a Phase I trial led by researchers at The...
by Virginia Commonwealth University Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer. Researchers from VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM)...
by University of British Columbia Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer Institute A new study from researchers at the University of British Columbia’s Faculty of Medicine reveals a direct link between high insulin levels, common among patients with obesity and type 2 diabetes, and pancreatic cancer....
By Michael Franco August 16, 2023 Although stick-like in its appearance, licorice root is quite different from the popular candy store treat Depositphotos Typically thought of as a bendy black confection, the root form of licorice has long been used in traditional Chinese medicine to treat a range of conditions. Now, a new study shows...
by Hong Kong Baptist University A research team led by Dr Joshua Ko Ka-shun, Associate Professor, Teaching and Research Division of the School of Chinese Medicine at HKBU, found that isoliquiritigenin, a herbal extract compound of the Chinese herbal medicine licorice, can inhibit pancreatic cancer progression. Credit: Hong Kong Baptist University Research led by scientists of...
AI model spots those at highest risk for up to three years before diagnosis Peer-Reviewed Publication HARVARD MEDICAL SCHOOL An artificial intelligence tool has successfully identified people at the highest risk for pancreatic cancer up to three years before diagnosis using solely the patients’ medical records, according to new research led by investigators at Harvard...
COLD SPRING HARBOR LABORATORY IMAGE: MOUSE PANCREAS CELLS WITH HIGH LEVELS OF THE PROTEIN SRSF1; CSHL PROFESSOR ADRIAN KRAINER FOUND THAT MICE WITH HIGH LEVELS OF SRFS1 TEND TO EXHIBIT INTRAEPITHELIAL NEOPLASIA—A KNOWN PRECURSOR TO THE MOST COMMON FORM OF PANCREATIC CANCER. CREDIT: KRAINER LAB/COLD SPRING HARBOR LABORATORY Pancreatic ductal adenocarcinoma (PDAC) is the most...
by Tim Tedeschi, University of Cincinnati Bacterial species diversity in long-term survivors (LTSs) versus controls. (A) Principal coordinates ordination performed on the species-level Bray-Curtis dissimilarity for LTSs and controls. (B) Shannon and Simpson indices for species diversity in LTSs versus controls. Credit: Cancer (2023). DOI: 10.1002/cncr.34748 Even as pancreatic cancer treatments improve, only about 9% of patients survive past five...
by Sylvester Comprehensive Cancer Center Credit: Unsplash/CC0 Public Domain Researchers have shown for the first time exactly how immature neutrophils—white blood cells that are an important part of the immune system—are hijacked by pancreatic cancers to drive immunosuppression and treatment resistance. The study, led by investigators at Sylvester Comprehensive Cancer Center at the University of Miami...
