by Brian Consiglio, University of Missouri Pancreatic cancer is rarely detected at its early stages because symptoms often do not present themselves until after the cancer has progressed. By then, invasive procedures such as surgery, chemotherapy or radiation are often needed to treat the cancer. Now, researchers at the University of Missouri’s College of Veterinary...
Tag: <span>Pancreatic cancer</span>
A surprising protein player in diabetes
by Okinawa Institute of Science and Technology A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University (OIST) and Riken Center of Integrative Medical Sciences. Called CNOT3, this protein was found...
Blocking nerve signals to the pancreas halts type 1 diabetes onset in mice
New LJI discovery could help explain patterns of cell death in many autoimmune diseases LA JOLLA INSTITUTE FOR IMMUNOLOGY LA JOLLA–Your pancreas is a little sweet potato-shaped organ that sits snug behind your stomach. The pancreas is studded with islets, the cell clusters that house insulin-producing beta cells. In people with type 1 diabetes, the...
Cancer diagnoses rates fell by half during US lockdown
particularly stark for breast cancer, which fell 51.8 percent during the lockdown compared to previous levels The number of cancers diagnosed weekly in the United States fell by almost fifty percent during March and April compared to the recent average, a study said Tuesday, the latest to examine the impacts of COVID-19 lockdowns. Emergency room...
Scientists discover novel drug target for pancreatic cancer
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE ANINDYA BAGCHI, PH.D., ASSOCIATE PROFESSOR IN THE TUMOR INITIATION AND MAINTENANCE PROGRAM AT SANFORD BURNHAM PREBYS. view more CREDIT: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Scientists at Sanford Burnham Prebys Medical Discovery Institute have uncovered a novel drug target, a protein called PPP1R1B, that stops the deadly spread of...
TGen identifies immune effects of drug in aggressive ovarian cancer striking young women
SP-2577 could enable the immune system to attack ovarian cancer; clinical trials for patients expected soon THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE PHOENIX, Ariz. — July 10, 2020 — A drug known as SP-2577 could help enable the body’s own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research...
Tongue microbes provide window to heart health
EUROPEAN SOCIETY OF CARDIOLOGY CLINICALLY, THERE ARE DIFFERENCES IN TONGUE IMAGES, INCLUDING TONGUE COATING AND TONGUE COLOUR BETWEEN CHRONIC HEART FAILURE (CHF) PATIENTS AND HEALTHY INDIVIDUALS. RECENT REPORTS HAVE SUGGESTED ALTERATIONS IN THE TONGUE… view more CREDIT: @EUROPEAN SOCIETY OF CARDIOLOGY 2020 Sophia Antipolis – 23 June 2020: Microorganisms on the tongue could help diagnose...
Diabetic mice improve with retrievable millimeter-thick cell-laden hydrogel fiber
INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO CREDIT: INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO Tokyo, Japan – Type 1 diabetes mellitus (T1DM) results from an irreversible autoimmune destruction of insulin-producing pancreatic β-cells requiring life-long substitution of insulin. In a new study, researchers at the Institute of Industrial Science, The University of Tokyo...
Researchers find a new therapeutic target in pancreatic cancer
by Dartmouth-Hitchcock Medical Center The development of pancreatic cancer is driven by co-existing mutations in an oncogene involved in controlling cell growth, called KRAS, and in a tumor suppressor gene, called p53. But how these mutations cooperate to promote cancer is unknown. A new study co-led by Steven Leach, MD, Director of Dartmouth’s and Dartmouth-Hitchcock’s...
First map of proinsulin’s ‘social network’ reveals new drug target for type 2 diabetes
Study reveals previously unknown protein that helps proinsulin fold and opens new avenues for diabetes research SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study,...