by International Society for Stem Cell Research Credit: CC0 Public Domain Recent advances in the transplantation of stem cell-derived insulin-producing beta cells (SC-beta cells) to treat type 1 diabetes (T1D) has generated considerable interest and excitement. A major obstacle to the long-term survival and functioning of SC-beta cells is their vulnerability to stress or attacks...
by Beth Newcomb, University of Southern California n mice that had been genetically engineered to develop autoimmune diabetes, “killer” T-cells (darker spots) infiltrate and destroy insulin-producing cells in the pancreas (left). Treatment with injections of MOTS-c reduced T-cell infiltration and prevented the onset of the disease (right). Credit: University of Southern California A new study has...
by University of Southern California Scientists develop new methods to peer deeply inside insulin-producing pancreas cells. Credit: Katya Kadyshevskaya For the first time, scientists have peered deeply inside a pancreatic cell and observed it packaging insulin and responding to a drug treatment, an intimate look at the mechanisms responsible for preventing diabetes. A team of scientists—led...
