Acute exudative pancreatitis on CT scan. Credit: Hellerhoff/Wikipedia Autoimmune pancreatitis (AIP) is a clinical condition characterized by inflammation of the pancreas, caused by the body’s hypersensitivity to its own proteins. AIP is typically accompanied by other organ inflammations such as autoimmune sialadenitis and cholangitis, together categorized as systemic autoimmune disorder, called IgG4-related disease (IgG4-RD). When...
Tag: <span>pancreatitis</span>
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Profiling pancreatitis
by Joel Streed, Mayo Clinic Credit: Pixabay/CC0 Public Domain Simply put, pancreatitis is inflammation of the pancreas. Located behind the stomach in the upper abdomen, your pancreas produces digestive enzymes and hormones that regulate how your body produces sugar. Pancreatitis is caused by the irritation and inflammation of the cells of your pancreas. This occurs when digestive enzymes released...
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Eating saturated fats found to reduce severity of pancreatitis
by Bob Yirka , Medical Xpress Credit: CC0 Public Domain A team of researchers from the Mayo Clinic, the Saint Louis University School of Medicine and the Washington University School of Medicine has found evidence that suggests people eating foods with saturated fats may have fewer symptoms if they develop pancreatitis. In their paper published in the...
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GLP-1-based treatment of diabetes does not cause pancreatitis
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES About 50,000 Danish diabetic patients are treated with GLP-1-based medicine. GLP-1 is a hormone that reduces the blood sugar and inhibits the appetite, and it is a frequent treatment for type 2 diabetes and obesity. A known side effect of this particular treatment is that...
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Study links obesity with pancreatitis
by Joe Dangor, Mayo Clinic A study by researchers at Mayo Clinic in Arizona published in the the Journal of Clinical Investigation has found that obesity is not only implicated in chronic diseases such as diabetes, but also in sudden-onset diseases such as pancreatitis. “In our study, we were able to demonstrate that fat within...
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Could pancreatitis be a stress hormone deficiency?
UT SOUTHWESTERN MEDICAL CENTER DALLAS – Jan. 8, 2020 – In work that could have clinical implications, UT Southwestern researchers find that humans and mice with pancreatitis are deficient in a stress hormone called FGF21. Normally, FGF21 is more abundant in the pancreas than in any other organ in the body. They also show that...
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Metformin may cut mortality risk in post-pancreatitis diabetes
Jaelim Cho, M.D., M.P.H., from the University of Auckland in New Zealand, and colleagues used nationwide pharmaceutical dispensing data (from 2006 to 2015) linked to hospital discharge data to identify 1,862 individuals with PCRD or PPDM. The researchers found that in individuals with PCRD, ever users of metformin (adjusted hazard ratio [aHR], 0.54) and ever users of insulin (aHR,...
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Sugars that coat proteins are a possible drug target for pancreatitis
by Cold Spring Harbor Laboratory Pancreatitis is an inflammation of the pancreas that accounts for 275,000 hospitalizations in the United States annually. Patients who suffer from hereditary pancreatitis have a 40 to 50 percent lifetime risk of developing pancreatic cancer. Dannielle Engle, a former Cold Spring Harbor Laboratory (CSHL) Cancer Center postdoctoral fellow who was recently appointed Assistant Professor...
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DPP-4I not tied to increased risk of acute pancreatitis in seniors
(HealthDay)—For older adults, dipeptidyl peptidase 4 inhibitors (DPP-4Is) are not associated with increased risk of acute pancreatitis, according to a study published online April 4 in Diabetes Care. Jin-Liern Hong, Ph.D., from the University of North Carolina at Chapel Hill, and colleagues examined the risks of acute pancreatitis among U.S. Medicare beneficiaries, aged 66+ years, initiating DDP-4Is versus...