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Scientists uncover key brain pathway mediating panic disorder symptoms

by Salk Institute PAC1R-expressing dorsal raphe neurons in the mouse brain (red) serve as the projection targets for PACAP parabrachial neurons to mediate panic-like behavioral and physical symptoms. Credit: Salk InstituteOverwhelming fear, sweaty palms, shortness of breath, rapid heart rate—these are the symptoms of a panic attack, which people with panic disorder have frequently and unexpectedly....