Tag: <span>paradigm</span>

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Keeping bone in its place

by Anivarya Kumar, Vanderbilt University Heterotopic ossification (HO) is the formation of bone within soft tissue such as muscle, leading to pain and potentially the inability to use a limb. Once thought to be primarily a genetic disease, the cause of most trauma-induced HO is unknown. Reporting this month in the journal Calcified Tissue International, Jonathan Schoenecker, MD,...

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Metastatic Colorectal Cancer Linked to Transcription Factors, Gene Networks

NEW YORK (GenomeWeb) – A pair of investigators from China has identified four transcription factors— along with related long non-coding RNAs and target genes — that are suspected of contributing to colorectal cancer (CRC) metastases. As they reported in Scientific Reports yesterday, the researchers used available RNA sequence, array-based genotype, DNA methylation, and mass spectrometry-based protein profile data to analyze samples from nearly 600...

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Magnetic Brain Stimulation: ‘Huge Amount of Promise’

TMS could still shift the psychiatric treatment paradigm, despite failure in VA trial In June, we reported on a disappointing trial of transcranial magnetic stimulation (TMS) for treatment-resistant depression, which found no advantage for the treatment over a sham version in a Veterans Affairs (VA) population. In this follow-up article, we take a look at...