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11 Symptoms That Could Be Early Signs of Parkinson’s Disease

Written by Katie E. Golden, MD | Reviewed by Patricia Pinto-Garcia, MD, MPH Updated on October 2, 2023 Key takeaways: The early signs of Parkinson’s disease can be subtle. They include loss of smell, constipation, trouble sleeping, and change in bladder habits.Many of the early symptoms of Parkinson’s start years before the more noticeable symptoms....

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NEUROSCIENTIST SAYS ‘BEWARE OF THESE 3 SUPPLEMENTS’ THAT CAN HARM YOUR BRAIN: ‘PARKINSON’S-LIKE SYMPTOMS

In the quest for better health, many people turn to supplements to fill nutritional gaps and boost their overall well-being. However, according to neuroscientist Robert Love, some commonly taken supplements can actually be harmful to your brain if consumed in high doses. In a TikTok video, Love warned about the potential dangers of three specific...

Another 3 common pesticides are now linked to Parkinson’s disease risk
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Another 3 common pesticides are now linked to Parkinson’s disease risk

Three more pesticides commonly used in the United States have now been linked to heightened Parkinson’s risk. Image credit: Abstract Aerial Art/Getty Images.Parkinson’s disease prevalence is growing fast, and similar to some other neurological conditions, its causes are unclear.The potential impact of chemicals that are toxic to neurons in the part of the brain affected...

Research reveals how a malfunctioning mechanism can lead to Parkinson’s disease
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Research reveals how a malfunctioning mechanism can lead to Parkinson’s disease

by Ruhr-Universitaet-Bochum NEMO is associated with pathological protein aggregates. Credit: Nature Communications (2023). DOI:10.1038/s41467-023-44033-0 Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson’s disease. NEMO, a protein that is primarily associated with signaling processes in the immune system, prevents the deposition of protein aggregates...

Four gut disorders associated with increased Parkinson’s risk
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Four gut disorders associated with increased Parkinson’s risk

By Paul McClure A study has found that four gut disorders are associated with an increased risk of developing Parkinson’s disease Depositphotos A new study has found that particular gastrointestinal disorders are associated with an increased risk of developing Parkinson’s disease. The research provides further evidence to support the hypothesis that the neurodegenerative disorder begins in...

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Study finds new pathway for clearing misfolded proteins

Peer-Reviewed Publication STANFORD UNIVERSITY Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer’s, Parkinson’s, and Huntington’s diseases. Cells work constantly to eliminate misfolded proteins, but these clearance mechanisms are still poorly understood. In a new study published April 20 in Nature Cell Biology, researchers at Stanford University discovered...

Treadmill exercise shown to improve Parkinson’s symptoms in mice
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Treadmill exercise shown to improve Parkinson’s symptoms in mice

by  Rush University Medical Center Credit: Debashis Dutta et al, Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111058 Regular treadmill exercise helped improve Parkinson’s disease symptoms in mice in a recent study by researchers at RUSH University Medical Center. The results of the study were recently published in the Cell Reports. “We’re very excited about the results,” said Kalipada Pahan, Ph.D., Floyd...

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Levodopa + carbidopa does not modify disease in early Parkinson

Constant V.M. Verschuur, M.D., from Amsterdam Neuroscience, and colleagues randomly assigned patients with early Parkinson disease to receive either levodopa (three times per day) in combination with carbidopa for 80 weeks (early-start group) or placebo for 40 weeks followed by levodopa in combination with carbidopa for 40 weeks (delayed-start group; 222 and 223 patients, respectively)....

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Investigational urate elevation does not appear to raise hypertension risk

Both phase 2 clinical trial results and animal model studies find no association between urate manipulation and blood pressure MASSACHUSETTS GENERAL HOSPITAL A study from a group of Massachusetts General Hospital (MGH) investigators may reduce the concern that elevated levels of urate, an approach being investigated to treat several neurodegenerative disorders, could increase the risk...

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Discovery of long-lived macrophages in the intestine

New prospects in the fight against neurodegenerative conditions KU LEUVEN Macrophages are specialized immune cells that destroy bacteria and other harmful organisms. KU Leuven scientists, Belgium, have come to the surprising conclusion that some macrophages in the intestines of mice can survive for quite some time. Most importantly, these long-lived macrophages are vital for the...

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