Scientists are testing new drug molecules to develop treatments for Parkinson’s disease. blue sky in my pocket/Getty ImagesResearchers have found that a novel drug molecule may fight the development of early-onset Parkinson’s disease in younger people.The new compound, BIO-2007817, is from the family of tetrahydropyrazolo-pyrazine (THPP) compounds.It offered promising results in activating parkin, a key...
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Unlocking the energy crisis in Parkinson’s: New findings offer hope for future treatment
News Release 26-Sep-2024 Scientists discover impaired energy recycling in Parkinson’s disease, opening the door for new therapies targeting purine recycling Peer-Reviewed PublicationFujita Health University Uric acid, inosine and hypoxanthine levels were found to be significantly lower in patients with Parkinson’s disease.Credit: Dr. Hirohisa Watanabe from Fujita Health University School of Medicine Parkinson’s disease (PD), the...
Study finds that dopaminergic medication improves sleep quality in Parkinson’s disease patients
August 13, 2024 by FAPESP Credit: Pixabay/CC0 Public DomainA study involving 22 Parkinson’s disease (PD) patients has shown that use of the dopaminergic drug levodopa improves sleep quality. When the patients took the drug, the number of times they woke up during the night fell 25% and the amount of time they remained awake fell...
Non-pharmacological interventions may play greater role in treatment of patients with Parkinson’s disease
August 13, 2024 by IOS Press Credit: Pixabay/CC0 Public DomainThe field of non-pharmacological interventions for the treatment of individuals with Parkinson’s disease (PD) is reaching maturity and has the potential to substantially improve patient care in the future. A supplement to the Journal of Parkinson’s Disease (JPD) captures a wealth of information on non-pharmacological interventions...
New video test for Parkinson’s uses AI to track how the disease is progressing
JULY 23, 2024 by Karen Dooley, University of Florida A patient performs the the finger-tapping test with Michael Jaffee, M.D., chair and professor of neurology at the University of Florida. Credit: UF Health A video-processing technique developed at the University of Florida that uses artificial intelligence will help neurologists better track the progression of Parkinson’s...
Molecular insights into cognitive impairment: New research uncovers how Parkinson’s affects the brain
JULY 11, 2024 by The Mount Sinai Hospital Image of a neuron that was part of the dataset. Credit: Mount Sinai Health SystemParkinson’s is associated with a higher risk of cognitive impairment and dementia that can severely impact quality of life. Cognitive symptoms include deficits in attention and mental flexibility, among others, and can pre-date...
New research links anxiety to higher Parkinson’s risk in over-50s
JUNE 24, 2024 by University College London Credit: Pixabay/CC0 Public DomainThe risk of developing Parkinson’s is at least twice as high in people with anxiety compared to those without, finds a new study by UCL researchers. The research, published in the British Journal of General Practice, investigated whether there was a link between people over...
Patients with Parkinson’s disease who experience freezing of gait have sleep disorders, study shows
by FAPESP Credit: Unsplash/CC0 Public DomainParkinson’s disease patients who experience freezing of gait (a sudden inability to initiate or continue movement, often resulting in a fall) wake up several times during the night, feel sleepy during the day, and have REM sleep behavior disorder. Rapid eye movement (REM) sleep plays a role in the maintenance of...
New research challenges conventional picture of Parkinson’s disease
by Arizona State University A new study highlights the role of misfolded tau proteins in the genesis and trajectory of Parkinson’s disease. Credit: Jason Drees for the Biodesign Institute at Arizona State UniversityParkinson’s disease, the second most common type of progressive dementia after Alzheimer’s disease, affects nearly 1 million people in the U.S. and an estimated...
This Small Wearable Device Reduces Parkinson’s Symptoms
People with Parkinson’s have fewer tremors when they receive rhythmic physical stimulation—so a UK startup has created a coin-sized vibrating device to help patients move more easily. PHOTOGRAPH: CHARCO NEUROTECH IN 2015, LUCY Jung was a young industrial designer working on assistive devices for stroke victims, people with multiple sclerosis, and those with other conditions...