By Dr. Liji Thomas, MD Mar 19 2023 Reviewed by Danielle Ellis, B.Sc. Parkinson’s disease (PD) is an incurable neurodegenerative disease that affects one in a hundred people the world over, second only to Alzheimer’s disease in the number of people affected. However, the mechanism by which it arises is still unclear. In a new research...
by Public Library of Science Drosophila that represents one of the models of neurodegeneration used in the lab to screen for things (both chemically and genetically) that regulate mitophagy. Credit: Angus McQuibban (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/) The words that researchers use to describe their results can be harnessed to discover potential new treatments for Parkinson’s disease, according to a...
by Ingrid Fadelli, Medical Xpress Credit: Zhang et al Proteins, long polymers comprised of smaller constituents known as amino acids, play a crucial role in the functioning of the human body. Over the course of a human’s life, these “strings” of proteins fold into unique 3D structures or conformations, and this folding process affects how...
by Abidemi Otaiku, The Conversation Credit: Pressmaster/Shutterstock Can children’s dreams foretell events that will happen nearly 40 years into the future? Yes, according to the results of my latest study published in the journal eClinicalMedicine. More specifically, it showed that children who experience regular bad dreams and nightmares between the ages of seven and 11, may...
by University of Queensland (A–E) Live imaging of non-stimulated and stimulated (30 min, 20 Hz) Drosophila larval NMJ boutons expressing Atg8mCherry at endogenous levels in the absence of Ca2+ (A and A′), presence of Ca2+ (B and B′), presence of EGTA-AM (no Ca2+ in the buffer) (C), and presence of DMSO plus Ca2+ (D). Fluorescence intensities shown using scale (0–1292 gray value)...
Marine Cygler January 23, 2023 PARIS ― Hallucinations affect more than half of patients with Parkinson’s disease. They are often hidden by those experiencing them, yet they are something neurologists must be made aware of in their patients, since they are associated with poor long-term outcomes and a reduced quality of life. Hallucinations also are a source of...
KAUNAS UNIVERSITY OF TECHNOLOGY IMAGE: DR RYTIS MASKELIŪNAS, A RESEARCHER AT KAUNAS UNIVERSITY OF TECHNOLOGY, KTU CREDIT: KTU The diagnosis of Parkinson’s disease has shaken many lives. More than 10 million people worldwide are living with it. There is no cure, but if symptoms are noticed early, the disease can be controlled. As Parkinson’s disease progresses, along...
by Parkinson’s Foundation Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia A new study reveals that the annual incidence of Parkinson’s disease (PD) among older adults is 50% higher than current estimates of 60,000 diagnoses annually. The peer-reviewed study, which measured new cases...
Stem Cell Therapy for Parkinson’s Disease Stem cell therapy may have the benefit of replacing and repairing damaged dopamine-producing nerve cells within the brain. This has already been found in a study conducted by Neelam K.Venkataramana and colleagues. Seven PD patients aged 22 to 62 years with a mean duration of disease 14.7 ± 7.56 years were...
by Bob Shepard, University of Alabama at Birmingham The study, utilizing the relatively new field of metagenomics, demonstrated an imbalance in the gut microbiome of patients with Parkinson’s disease. Credit: University of Alabama at Birmingham New research from the University of Alabama at Birmingham says the gut microbiome is involved in multiple pathways in the...
