by La Jolla Institute for Immunology roducing brain cells of patients with Parkinson’s disease. T cells that react to alpha-synuclein are most abundant when patients are first diagnosed with the disease. Credit: La Jolla Institute for Immunology A new study co-led by scientists at the La Jolla Institute for Immunology (LJI) adds increasing evidence that...
Exercise has potential to improve non-motor as well as motor symptoms of Parkinson’s disease (PD), including cognitive function, report investigators in a review published in the Journal of Parkinson’s Disease. PD is a slowly progressive disorder that affects movement, muscle control, and balance. While traditionally regarded as a movement disorder, it is now known to be a heterogeneous multisystem disorder – in recognition of the significant impact that non-motor symptoms have...
For the first time, MIT researchers have shown that nerves made to express proteins that can be activated by light can produce limb movements that can be adjusted in real-time, using cues generated by the motion of the limb itself. The technique leads to movement that is smoother and less fatiguing than similar electrical systems...
Constipation is one of the most common non-motor related complaints affecting Parkinson’s disease (PD) patients. Two important studies from the same research group published in the Journal of Parkinson’s Diseaseexpand the understanding of the relationship between PD and gastrointestinal dysfunction. In one study, investigators measured actual colonic dysfunction and compared it to reported constipation. In the...
Dopamine neurons degenerate and die in the brains of people suffering from Parkinson’s disease. Researchers at Karolinska Institutet have made significant progress in the search for new treatments for Parkinson’s disease. By manipulating the gene expression of non-neuronal cells in the brain, they were able to produce new dopamine neurons. The study, performed on...
Statistics show that 25 per cent of recently diagnosed patients suffered a fall in the first year. That came as a surprise to researchers. They had thought that falls tended to occur during later stages of the disease. Fetching the shopping bags out of the car, going up the stairs, finding the house keys, locating...
