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Game-changer for Parkinson’s disease outcomes

July 10, 2018 by Robyn Mills, University of Adelaide A unique gaming system called ‘OrbIT’ will play a lead role in the fight to improve life for individuals living with Parkinson’s disease, thanks to funding from the Estate of the late Olga Mabel Woolger. Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in...

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Half of those on Parkinson’s drugs may develop impulse control problems

Over time, half of the people taking certain drugs for Parkinson’s disease may develop impulse control disorders such as compulsive gambling, shopping or eating, according to a study published in the June 20, 2018, online issue of Neurology. Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease....

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Scientists unravel molecular mechanisms of Parkinson’s disease

Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson’s disease. The study, published in Nature Communications, adds to our growing understanding of the causes of Parkinson’s and other neurodegenerative diseases, and could influence drug design in the future. For years, scientists have known that Parkinson’s disease is associated with a build-up of alpha-synuclein protein...

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Bacteriophages: Are they an overlooked driver of Parkinson’s disease?

In the first study of its kind, researchers from the New York-based Human Microbiology Institute have discovered the role certain bacteriophages may play in the onset of Parkinson’s disease (PD). The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th to June 11th in Atlanta, Georgia. The researchers, led by...

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Imec Develops Wireless Eye-Tracking Glasses to Aid in Research of Neurological Disorders

Many neurodegenerative diseases, such as Parkinson’s and Alzheimer’s, can often present with symptoms of abnormal eye movements. Much research has been done in utilizing eye movement tracking technology to help with the diagnosis of these diseases and the monitoring of their progression. Traditional eye-tracking technology relies heavily on cameras, which, while accurate, are typically large...

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World first use of cognitive training reduces gait freezing in Parkinson’s patients

Research led by the University of Sydney’s Brain and Mind Centre, published today npj Parkinson’s Disease — Nature UNIVERSITY OF SYDNEY The researchers report significant reduction in the severity and duration of freezing of gait, improved cognitive processing speed and reduced daytime sleepiness. Freezing of gait (FoG) is a disabling symptom of Parkinson’s Disease, characterized by patients becoming...

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New study sheds light on the complex dynamics of Parkinson’s disease

Mark Schnitzer and other Stanford researchers have found the truth is more complicated than a seminal theory of Parkinson’s disease suggested. Credit: L.A. Cicero Parkinson’s disease affects around 10 million people worldwide, yet exactly how the disease and treatments for its symptoms work remains a bit mysterious. Now, Stanford researchers have tested a seminal theory of Parkinson’s and found...

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Parkinson, Depression Meds Tied to Dementia Risk

Associations persisted up to 2 decades after exposure Long-term use of anticholinergic medications for Parkinson’s disease, bladder conditions, and depression was associated with an increased risk for dementia, a case-control study found. For drugs previously associated with delirium, the highest odds were seen with anticholinergic drugs for Parkinson’s (adjusted OR 1.29, 95% CI 1.11-1.50, P<0.01) and...

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Key factor in development of Parkinson’s disease identified

Purdue University researchers Jean-Christophe “Chris” Rochet and Dr. Riyi Shi say their discovery of a key factor in the development of Parkinson’s disease could lead to new therapies, potentially including drugs currently on the market; A molecule has been identified that appears to play an important role in the development of Parkinson’s disease, a debilitating disease that...