Rice engineering students have designed an iPhone app to help patients overcome a symptom known as “freezing,” in which the legs temporarily refuse to follow the brain’s command to lift and move forward. In visual mode, the app places It’s appropriate that during Parkinson’s Awareness Month, a team of Rice University seniors will show how...
Tag: <span>parkinsons</span>
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Protein analysis for personalised medicine
New knowledge about proteins helps researchers develop innovative solutions for clinical practice, for example to the benefit of patients with Parkinsons’s disease. To this day, there are no therapies that work equally well for all patientsdiagnosed with the same disease. Many conventional therapies are effective in only a limited proportion of cases. And some patients who...
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Faulty Cellular Membrane “Mix” Linked To Parkinson’s Disease
Working with lab-grown human brain cells, Johns Hopkins researchers report they have uncovered a much sought-after connection between one of the most common genetic mutations in Parkinson’s disease and the formation of fatty plaques in the brain thought to contribute to the destruction of motor neurons that characterize the disease. The mutation occurs in a...
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Cognitive status doesn’t impact cortical A-beta, tau in Parkinson’s
(HealthDay)—Patterns of cortical β-amyloid (Aβ) and tau are not different for patients with Parkinson’s disease (PD) who are cognitively normal (PD-CN) or with mild cognitive impairment (MCI) and for healthy adults, according to a study published online Dec. 11 in JAMA Neurology. Joseph R. Winer, from the University of California in Berkeley, and colleagues conducted a...
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High-intensity exercise delays Parkinson’s progression
Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. High-intensity exercise three times a week is safe for individuals with early-stage Parkinson’s disease and decreases worsening of motor symptoms, according to a new phase 2, multi-site trial led by Northwestern Medicine and University of Denver...
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Newly Described Process in Parkinson’s Protein as a Potential New Therapy Route
An international group of researchers led by Professor Wim Versées (VIB-VUB) has unraveled the workings of an essential mechanism in ‘Parkinson’s protein’ LRRK2. Their study demonstrates a direct link between the protein’s ‘dimerization’ – two copies that are bound together -and mutations that lead to Parkinson’s disease. This process could eventually lead to a promising...
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Scientists discover why Parkinson’s sufferers like Robin Williams may suffer hallucinations
Parkinson’s patients with hallucinations have disconnections between more areas of their brains than Parkinson’s patients without hallucinations The additional disconnections are between areas of the brain controlling the ability to process visual information and to pay attention MRI scans could help doctors detect increased disconnections that may lead to hallucinations in Parkinson’s patients These new...
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Highest adverse effect rates for three drugs in parkinson’s
(HealthDay)—Ropinirole, bromocriptine, and piribedil are associated with the highest incidence rates of adverse effects in Parkinson’s disease, according to a review published online Sept. 4 in CNS Neuroscience & Therapeutics. Bao-Dong Li, from the Hebei Province Cangzhou Hospital of Integrated Traditional and Western Medicine in China, and colleagues conducted a systematic review to compare the adverse effects of 11 drugs...
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Psychosis in Parkinson’s dementia—new treatment provides hope
New research involving King’s College London and the University of Exeter has highlighted the benefits of a promising new treatment which could relieve psychosis in thousands of people with dementia related to Parkinson’s disease. Around 80 per cent of people with Parkinson’s disease develop dementia, totalling around 100,000 people in the UK. ,The majority of these...
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New drugs and treatments for Parkinson’s, but where are the doctors?
For many, hearing the word “Parkinson’s” conjures an image of tremors. But Parkinson’s disease, brought about by loss of nerve and other brain cells, is actually an incredibly complex movement disorder that can cause symptoms as wide-ranging as smell loss, thinking issues, depression and swallowing problems. More than 1.5 million people in the U.S. have the...