by Texas A&M University Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Texas A&M University College of Medicine ressearchers have recently discovered that cytisine—a smoking cessation drug commonly used in Europe—reduces the loss of dopamine neurons in females. These findings provide potential evidence for...
by University of Cambridge 3D illustration showing neurons containing Lewy bodies small red spheres which are deposits of proteins accumulated in brain cells that cause their progressive degeneration. Credit: Kateryna Kon via Shutterstock A study published in Nature Communications today presents a compelling new evidence about what a key protein called alpha-synuclein actually does in neurons in the...
VAN ANDEL RESEARCH INSTITUTE GRAND RAPIDS, Mich. (Feb. 2, 2021) — What does bile acid production in the digestive tract have to do with Parkinson’s disease? Quite a lot, according to a sweeping new analysis published in the journal Metabolites. The findings reveal that changes in the gut microbiome — the rich population of helpful microbes that call the...
Necessity has long been the mother of invention, but thanks to cutting-edge technology and the power of social media, the leap from inspiration to reality can happen almost overnight. If you doubt it, just ask Jimmy Choi. Pill bottle, Brian Alldridge; Jimmy Choi Choi is an amazing athlete. He also suffers from Parkinson’s disease. Diagnosed...
UNIVERSITY COLLEGE LONDON Simple vision tests can predict which people with Parkinson’s disease will develop cognitive impairment and possible dementia 18 months later, according to a new study by UCL researchers. The study, published in Movement Disorders, adds to evidence that vision changes precede the cognitive decline that occurs in many, but not all, people with...
by Ruhr-Universitaet-Bochum Magnetically, the nanoparticles found their way into the tips of the processes of nerve cells. Credit: Molekulare Neurobiochemie One reason why nerve damage in the brain cannot regenerate easily is that the neurites do not know in which direction they should grow. A team of researchers from Ruhr-Universität Bochum (RUB), Sorbonne University Paris, and the Technische...
by University College London Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Elevated risk of Parkinson’s disease among people with type 2 diabetes appears to be reduced by some medications used to treat their diabetes, finds a new study led by UCL researchers. The researchers are testing one of...
by Eric Hamilton, University of Wisconsin-Madison The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson’s. Stem cells, which are endlessly adaptable, have offered the promise of better neural repair. But the brain’s precisely tuned complexity has stymied the development of clinical...
by University of Turku A. The first panel shows the relative levels of protein synthesis in cells from healthy donors compared to those from two classes of Parkinson’s patients; those carrying a gain of function LRRK2-G2019S mutation and sporadic cases, the most common form which is not directly inherited. Protein synthesis was reduced in both groups....
by Queen Mary, University of London Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Including genetic markers in addition to well known risk factors improves tests to predict Parkinson’s disease, according to a study led by Queen Mary University of London. Parkinson’s disease is...
