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Trials begin for a new weapon against Parkinson’s: light
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Trials begin for a new weapon against Parkinson’s: light

By Gunjan Sinha Light therapy can help lift moods, heal wounds, and boost the immune system. Can it improve symptoms of Parkinson’s disease, too? A first-of-its-kind trial scheduled to launch this fall in France aims to find out. In seven patients, a fiber optic cable implanted in their brain will deliver pulses of near-infrared (NIR) light...

NexStride Helps Overcome Freeze of Gait in Parkinson’s
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NexStride Helps Overcome Freeze of Gait in Parkinson’s

People with Parkinson’s disease and some other neurological disorders often suffer from a condition known as freezing of gait. For poorly understood reasons, initiating a step is often a challenge. Patients report a feeling of disassociation between one’s will to move and the legs not responding accordingly. This is both frustrating and can lead to...

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New vitamin K-based drug shows promise against medication-resistant epilepsy

Researchers at the Medical University of South Carolina have formulated a vitamin K-based compound that, due to its unique structure and mechanism, eliminates medication-resistant epileptic seizures in mice tested to date. Credit: Sarah Pack, Medical University of South Carolina In the cover article of the June 11 issue of the Journal of Medicinal Chemistry, a...

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Pint-sized molecule could slip through the gaps to tackle Parkinson’s

The progression of Parkinson’s disease is characterized by a reduced ability of the brain to produce dopamine, a neurotransmitter responsible for the messaging that controls body movement. For this reason, much research in the area concentrates on developing therapies that can arrest this slide, and scientists in Finland have now uncovered a promising path forward...

Wearable tech can provide better data for Parkinson’s
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Wearable tech can provide better data for Parkinson’s

by Tim Sullivan, Harvard Medical School3 Wearable technology and other mobile data-gathering devices should replace self-reporting diaries to track symptoms in people with Parkinson’s disease, a new study from a large industry and academic collaboration argues. The study was published January 17 in npj Digital Medicine. “For clinicians to effectively manage the diseaseand for researchers...

Parkinson’s and the immune system
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Parkinson’s and the immune system

Medicine RUHR-UNIVERSITY BOCHUM The team was thus able to provide further evidence that there are interfaces between the nervous system and immune system. The researchers hope that the protagonists or antagonists of this signalling pathway may be suitable for therapeutic interventions. They report on this in the cover story in the journal Science Signalingon 4...

Gene ID’d as potential therapeutic target for dementia in Parkinson’s
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Gene ID’d as potential therapeutic target for dementia in Parkinson’s

by Washington University School of Medicine Dementia is one of the most debilitating consequences of Parkinson’s disease, a progressive neurological condition characterized by tremors, stiffness, slow movement and impaired balance. Eighty percent of people with Parkinson’s develop dementia within 20 years of the diagnosis, and patients who carry a particular variant of the gene APOE...