by Hong Kong Polytechnic University C57BL6 mice were inoculated with 104 CFU of indicated Kp strains and the Kaplan–Meier survival curve was recorded. n = 10/group. b Spleen weight and representative image of spleens harvested from Kp-infected mice. c Bacterial load in various organs of mice at 12 hpi. n = 5/group. d Cell suspensions recovered from the lungs and...
By Dr. Tomislav Meštrović, MD, Ph.D. May 31 2021 In a new research paper currently available on the bioRxiv* preprint server, a research group from the United Kingdom (UK) provides experimental evidence that B.1.617 lineage of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) – also known as the Indian variant of concern – shows...
by Walter and Eliza Hall Institute of Medical Research Iron is an important component of the protein haemoglobin, which is contained in red blood cells and carries oxygen around the body. Credit: Haemoglobin and Sickle Cell Anaemia WEHI.TV animation. A new iron intervention study has determined which of the world’s low-and-middle income countries would benefit...
GEOMAR research group successfully applies bioinformatics methods and machine learning in marine drug discovery HELMHOLTZ CENTRE FOR OCEAN RESEARCH KIEL (GEOMAR) BALTIC SEA SEAWEED FUCUS VESICULOSUS AND ITS FUNGAL SYMBIONT WERE INVESTIGATED IN THIS STUDY. view more CREDIT: LARISSA BÜDENBENDER Healing with the help of marine organisms is no utopia. Already 12 life-saving drugs, e.g....
Kazan Federal University continues to research Staphylococcus aureus, one of the most dangerous bacteria causing nosocomial infections. It is well known that many strains of Staphylococcus are resistant to antibiotics, and research groups around the world seek new targets in the bacteria to decrease their infectious potential. Head of KFU research group, Leading Research Associate...
Expanding the Organismal Proteostasis Network: Linking Systemic Stress Signaling with the Innate Immune Response Jay Miles Ruth Scherz-Shouval Patricija van Oosten-Hawle Open AccessPublished:July 11, 2019DOI:https://doi.org/10.1016/j.tibs.2019.06.009 PlumX Metrics Previous Article Nature and Regulation of Protein Folding on th … Next Article Analysis and Interpretation of Protein Post-Translational M … Highlights Keywords The Cellular and Organismal Proteostasis...
by University of Bristol With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections. Candida albicans, a well-known yeast usually seen in the mouth, skin, gut and vagina, is reported to form biofilms...
University of Alabama at Birmingham researchers have found a novel, previously unreported pathogenic entity that is a fundamental link between chronic inflammation and tissue destruction in the lungs of patients with chronic obstructive pulmonary disease, or COPD. COPD is the fourth-leading cause of death in the world. Credit: CC0 Public Domain This pathogenic entity—exosomes from...
Summary: Multiple sclerosis is an autoimmune disease in which the body’s immune system attacks the patient’s own cells. In this case, modified T cells destroy the myelin sheath surrounding nerve cells. Myelin protects the neural pathways and is thus essential to the ability of nerve cells to transmit information. A recent study has demonstrated that...
