by Silvia Cernea Clark, Rice University Schematic representation of the mechanisms of action of antifungal MMs. MMs bind cardiolipin and phosphatidylglycerol in the inner mitochondrial membrane, destabilizing the electron transport chain. This leads to increased electron leakage and superoxide radical formation, causing oxidative stress. Consequently, ATP synthesis and mitochondrial membrane potential are reduced. ATP-dependent calcium transporters...
Tag: <span>pathogenic fungi</span>
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Structures involved in communication among pathogenic fungi could be targets for novel treatments
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO A group of scientists in Brazil and the United States has revealed the role played by certain structures in intermediating communication among individual fungi of the same species. The discovery, detailed in an article published in the journal mBio, could serve as the basis for...