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Gut microbes may determine patients’ response to a drug that delays onset of type 1 diabetes
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Gut microbes may determine patients’ response to a drug that delays onset of type 1 diabetes

by Delthia Ricks , Medical Xpress Teplizumab delays type 1 diabetes (T1D) in at-risk individuals in TN10 trial, but participants respond differently to the treatment. Systemic, non-pathogenic antibody responses to gut bacteria can be quantified by anti-commensal antibody (ACAb) assay. Individuals with higher IgG2 responses to specific gut bacteria are more likely to get early...